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Neoantigen-reactive CD8+ T cells affect clinical outcome of adoptive cell therapy with tumor-infiltrating lymphocytes in melanoma.
Kristensen, Nikolaj Pagh; Heeke, Christina; Tvingsholm, Siri A; Borch, Annie; Draghi, Arianna; Crowther, Michael D; Carri, Ibel; Munk, Kamilla K; Holm, Jeppe Sejerø; Bjerregaard, Anne-Mette; Bentzen, Amalie Kai; Marquard, Andrea M; Szallasi, Zoltan; McGranahan, Nicholas; Andersen, Rikke; Nielsen, Morten; Jönsson, Göran B; Donia, Marco; Svane, Inge Marie; Hadrup, Sine Reker.
Affiliation
  • Kristensen NP; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Heeke C; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Tvingsholm SA; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Borch A; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Draghi A; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
  • Crowther MD; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
  • Carri I; Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Buenos Aires, Argentina.
  • Munk KK; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Holm JS; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Bjerregaard AM; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Bentzen AK; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Marquard AM; Section for Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark (DTU), Kongens Lyngby, Denmark.
  • Szallasi Z; Danish Cancer Society Research Center, Copenhagen, Denmark.
  • McGranahan N; Cancer Genome Evolution Research Group, University College London Cancer Institute, London, United Kingdom.
  • Andersen R; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
  • Nielsen M; Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Buenos Aires, Argentina.
  • Jönsson GB; Section for Bioinformatics, Department of Health Technology, DTU, Kongens Lyngby, Denmark.
  • Donia M; Division of Oncology and Pathology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden.
  • Svane IM; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
  • Hadrup SR; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.
J Clin Invest ; 132(2)2022 01 18.
Article de En | MEDLINE | ID: mdl-34813506
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Activation des lymphocytes / Lymphocytes TIL / Lymphocytes T CD8/ / Transfert adoptif / Mélanome / Antigènes néoplasiques Type d'étude: Clinical_trials / Prognostic_studies Limites: Female / Humans / Male Langue: En Journal: J Clin Invest Année: 2022 Type de document: Article Pays d'affiliation: Danemark Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Activation des lymphocytes / Lymphocytes TIL / Lymphocytes T CD8/ / Transfert adoptif / Mélanome / Antigènes néoplasiques Type d'étude: Clinical_trials / Prognostic_studies Limites: Female / Humans / Male Langue: En Journal: J Clin Invest Année: 2022 Type de document: Article Pays d'affiliation: Danemark Pays de publication: États-Unis d'Amérique