Discovery of Novel Polycyclic Heterocyclic Derivatives from Evodiamine for the Potential Treatment of Triple-Negative Breast Cancer.

Xu, Shengtao; Yao, Hong; Qiu, Yangyi; Zhou, Manzhen; Li, Dahong; Wu, Liang; Yang, Dong-Hua; Chen, Zhe-Sheng; Xu, Jinyi

Xu, Shengtao; Yao, Hong; Qiu, Yangyi; Zhou, Manzhen; Li, Dahong; Wu, Liang; Yang, Dong-Hua; Chen, Zhe-Sheng; Xu, Jinyi.

Affiliation

Xu S; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Yao H; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Qiu Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Zhou M; Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Kowloon, Hong Kong 999077, P. R. China.
Li D; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Wu L; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Yang DH; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, P. R. China.
Chen ZS; Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Xu J; College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, New York 11439, United States.

J Med Chem ; 64(23): 17346-17365, 2021 12 09.

Article de En | MEDLINE | ID: mdl-34844412

Sujet(s)

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Composés polycycliques / Quinazolines / Tumeurs du sein triple-négatives / Composés hétérocycliques / Antinéoplasiques Limites: Female / Humans Langue: En Journal: J Med Chem Sujet du journal: QUIMICA Année: 2021 Type de document: Article

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google