Compressive stress-mediated p38 activation required for ER&#945; + phenotype in breast cancer.

Munne, Pauliina M; Martikainen, Lahja; Räty, Iiris; Bertula, Kia; Ruuska, Janika; Ala-Hongisto, Hanna; Peura, Aino; Hollmann, Babette; Euro, Lilya; Yavuz, Kerim; Patrikainen, Linda; Salmela, Maria; Pokki, Juho; Kivento, Mikko; Väänänen, Juho; Suomi, Tomi; Nevalaita, Liina; Mutka, Minna; Kovanen, Panu; Leidenius, Marjut; Meretoja, Tuomo; Hukkinen, Katja; Monni, Outi; Pouwels, Jeroen; Sahu, Biswajyoti; Mattson, Johanna; Joensuu, Heikki; Heikkilä, Päivi; Elo, Laura L; Metcalfe, Ciara; Junttila, Melissa R; Ikkala, Olli; Klefström, Juha

Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer.

Munne, Pauliina M; Martikainen, Lahja; Räty, Iiris; Bertula, Kia; Ruuska, Janika; Ala-Hongisto, Hanna; Peura, Aino; Hollmann, Babette; Euro, Lilya; Yavuz, Kerim; Patrikainen, Linda; Salmela, Maria; Pokki, Juho; Kivento, Mikko; Väänänen, Juho; Suomi, Tomi; Nevalaita, Liina; Mutka, Minna; Kovanen, Panu; Leidenius, Marjut; Meretoja, Tuomo; Hukkinen, Katja; Monni, Outi; Pouwels, Jeroen; Sahu, Biswajyoti; Mattson, Johanna; Joensuu, Heikki; Heikkilä, Päivi; Elo, Laura L; Metcalfe, Ciara; Junttila, Melissa R; Ikkala, Olli; Klefström, Juha.

Affiliation

Munne PM; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Martikainen L; Department of Applied Physics, Molecular Materials Group, Aalto University School of Science, PO Box, 15100, FI-00076, Espoo, Finland.
Räty I; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Bertula K; Department of Applied Physics, Molecular Materials Group, Aalto University School of Science, PO Box, 15100, FI-00076, Espoo, Finland.
Nonappa; Department of Applied Physics, Molecular Materials Group, Aalto University School of Science, PO Box, 15100, FI-00076, Espoo, Finland.
Ruuska J; Department of Bioproducts and Biosystems, Aalto University School of Chemical Engineering, Espoo, Finland.
Ala-Hongisto H; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Peura A; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Hollmann B; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Euro L; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Yavuz K; Research Program of Stem Cells and Metabolism, Biomedicum Helsinki, University of Helsinki, 00290, Helsinki, Finland.
Patrikainen L; Applied Tumor Genomics Research Program, Enhancer Biology Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Salmela M; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Pokki J; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Kivento M; Department of Electrical Engineering and Automation, Aalto University, Espoo, Finland.
Väänänen J; Applied Tumor Genomics Research Program, Faculty of Medicine, Oncogenomics Laboratory, University of Helsinki, Helsinki, Finland.
Suomi T; Applied Tumor Genomics Research Program, Faculty of Medicine, Oncogenomics Laboratory, University of Helsinki, Helsinki, Finland.
Nevalaita L; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.
Mutka M; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Kovanen P; Department of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
Leidenius M; Department of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
Meretoja T; Breast Surgery Unit, Helsinki University Central Hospital, Helsinki, Finland.
Hukkinen K; Breast Surgery Unit, Helsinki University Central Hospital, Helsinki, Finland.
Monni O; Department of Mammography, Helsinki University Central Hospital, Helsinki, Finland.
Pouwels J; Applied Tumor Genomics Research Program, Faculty of Medicine, Oncogenomics Laboratory, University of Helsinki, Helsinki, Finland.
Sahu B; Finnish Cancer Institute, FICAN South Helsinki University Hospital & Translational Cancer Medicine, Medical Faculty, University of Helsinki. Cancer Cell Circuitry Laboratory, PO Box 63 Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
Mattson J; Applied Tumor Genomics Research Program, Enhancer Biology Laboratory, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Joensuu H; Department of Oncology, University of Helsinki & Helsinki University Hospital, Helsinki, Finland.
Heikkilä P; Department of Oncology, University of Helsinki & Helsinki University Hospital, Helsinki, Finland.
Elo LL; Department of Pathology, HUSLAB and Haartman Institute, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
Metcalfe C; Turku Bioscience Centre, University of Turku and Åbo Akademi University, FI-20520, Turku, Finland.
Junttila MR; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Ikkala O; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Klefström J; Department of Applied Physics, Molecular Materials Group, Aalto University School of Science, PO Box, 15100, FI-00076, Espoo, Finland.

Nat Commun ; 12(1): 6967, 2021 11 29.

Article de En | MEDLINE | ID: mdl-34845227

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du sein / Mécanotransduction cellulaire / P38 Mitogen-Activated Protein Kinases / Récepteur alpha des oestrogènes / Transcriptome Type d'étude: Observational_studies / Prognostic_studies / Risk_factors_studies Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2021 Type de document: Article Pays d'affiliation: Finlande Pays de publication: Royaume-Uni

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