Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease.

Maestro, Inés; de la Ballina, Laura R; Simonsen, Anne; Boya, Patricia; Martinez, Ana

Maestro, Inés; de la Ballina, Laura R; Simonsen, Anne; Boya, Patricia; Martinez, Ana.

Affiliation

Maestro I; Centro de Investigaciones Biologicas Margarita Salas-CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
de la Ballina LR; Centro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain.
Simonsen A; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.
Boya P; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.
Martinez A; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, 0372 Oslo, Norway.

ACS Chem Neurosci ; 12(24): 4512-4523, 2021 12 15.

Article de En | MEDLINE | ID: mdl-34846852

Sujet(s)
Mots clés

Parkinson's disease; drug discovery; mitophagy; mitophagy inducers; phenotypic assay

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladie de Parkinson / Mitophagie Limites: Humans Langue: En Journal: ACS Chem Neurosci Année: 2021 Type de document: Article Pays d'affiliation: Espagne Pays de publication: États-Unis d'Amérique

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