Allosteric Modulation of the Sigma-1 Receptor Elicits Antipsychotic-like Effects.

Chen, Jiali; Li, Guangying; Qin, Pingping; Chen, Jiaojiao; Ye, Na; Waddington, John L; Zhen, Xuechu

Chen, Jiali; Li, Guangying; Qin, Pingping; Chen, Jiaojiao; Ye, Na; Waddington, John L; Zhen, Xuechu.

Affiliation

Chen J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Li G; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Qin P; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Chen J; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Ye N; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Waddington JL; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China.
Zhen X; School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland.

Schizophr Bull ; 48(2): 474-484, 2022 03 01.

Article de En | MEDLINE | ID: mdl-34865170

Sujet(s)
Mots clés

AKTCREBBDNF pathway; SOMCL-668; allosteric modulator; chaperone protein; schizophrenia

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Neuroleptiques / Récepteur sigma / Régulation allostérique Limites: Animals Langue: En Journal: Schizophr Bull Année: 2022 Type de document: Article Pays d'affiliation: Chine

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