Encapsulation of doxorubicin prodrug in heat-triggered liposomes overcomes off-target activation for advanced prostate cancer therapy.

Pereira, Sara; Ma, Guanglong; Na, Li; Hudoklin, Samo; Kreft, Mateja E; Kostevsek, Nina; Al-Jamal, Wafa T

Pereira, Sara; Ma, Guanglong; Na, Li; Hudoklin, Samo; Kreft, Mateja E; Kostevsek, Nina; Al-Jamal, Wafa T.

Affiliation

Pereira S; School of Pharmacy, Queen's University Belfast, United Kingdom.
Ma G; School of Pharmacy, Queen's University Belfast, United Kingdom.
Na L; School of Pharmacy, Queen's University Belfast, United Kingdom.
Hudoklin S; University of Ljubljana, Faculty of Medicine, Institute of Cell Biology, Ljubljana, Slovenia.
Kreft ME; University of Ljubljana, Faculty of Medicine, Institute of Cell Biology, Ljubljana, Slovenia.
Kostevsek N; Department for Nanostructured Materials, Jozef Stefan Institute, Ljubljana, Slovenia.
Al-Jamal WT; School of Pharmacy, Queen's University Belfast, United Kingdom. Electronic address: w.al-jamal@qub.ac.uk.

Acta Biomater ; 140: 530-546, 2022 03 01.

Article de En | MEDLINE | ID: mdl-34954416

Sujet(s)
Mots clés

Cardiotoxicity; Doxorubicin prodrug; Hyperthermia; Low temperature-sensitive liposomes; Prostate cancer; Prostate-specific antigen (PSA); Targeted therapy

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs de la prostate / Promédicaments Limites: Animals / Humans / Male Langue: En Journal: Acta Biomater Année: 2022 Type de document: Article Pays d'affiliation: Royaume-Uni

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