Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats.

Khom, Sophia; Rodriguez, Larry; Gandhi, Pauravi; Kirson, Dean; Bajo, Michal; Oleata, Christopher S; Vendruscolo, Leandro F; Mason, Barbara J; Roberto, Marisa

Khom, Sophia; Rodriguez, Larry; Gandhi, Pauravi; Kirson, Dean; Bajo, Michal; Oleata, Christopher S; Vendruscolo, Leandro F; Mason, Barbara J; Roberto, Marisa.

Affiliation

Khom S; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America; Department of Pharmaceutical Sciences, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
Rodriguez L; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America.
Gandhi P; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America.
Kirson D; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America; Department of Pharmacology, Addiction Science, and Toxicology, University of Tennessee Health Science Center, 71 S Manassas, Memphis, TN 38163, United States of America.
Bajo M; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America.
Oleata CS; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America.
Vendruscolo LF; Integrative Neuroscience Research Branch, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd., Baltimore, MD 21224, United States of America.
Mason BJ; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America.
Roberto M; Department of Molecular Medicine, Scripps Research, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, United States of America. Electronic address: mroberto@scripps.edu.

Neurobiol Dis ; 164: 105610, 2022 03.

Article de En | MEDLINE | ID: mdl-34995754

Sujet(s)
Mots clés

Alcohol use disorder; Central amygdala; Electrophysiology; GABA; Glucocorticoid receptors; Mifepristone; Synaptic transmission; eIPSP; sIPSC

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Synapses / Récepteurs aux glucocorticoïdes / Mifépristone / Alcoolisme / Neurones GABAergiques / Antihormones / Amygdale (système limbique) Type d'étude: Diagnostic_studies Limites: Animals Langue: En Journal: Neurobiol Dis Sujet du journal: NEUROLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Autriche Pays de publication: États-Unis d'Amérique

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google