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GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment.
Gabe, Maria Buur Nordskov; Skov-Jeppesen, Kirsa; Gasbjerg, Lærke Smidt; Schiellerup, Sine Pasch; Martinussen, Christoffer; Gadgaard, Sarina; Boer, Geke Aline; Oeke, Jannika; Torz, Lola Julia; Veedfald, Simon; Svane, Maria Saur; Bojsen-Møller, Kirstine Nyvold; Madsbad, Sten; Holst, Jens Juul; Hartmann, Bolette; Rosenkilde, Mette Marie.
Affiliation
  • Gabe MBN; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Skov-Jeppesen K; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Gasbjerg LS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Schiellerup SP; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Martinussen C; Department of Endocrinology, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
  • Gadgaard S; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Boer GA; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Oeke J; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Torz LJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Veedfald S; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Svane MS; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Department of Endocrinology, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
  • Bojsen-Møller KN; Department of Endocrinology, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
  • Madsbad S; Department of Endocrinology, Copenhagen University Hospital Hvidovre, 2650 Hvidovre, Denmark.
  • Holst JJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.
  • Hartmann B; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address: bhartmann@sund.ku.dk
  • Rosenkilde MM; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address: rosenkilde@sund.ku.dk.
Pharmacol Res ; 176: 106058, 2022 02.
Article de En | MEDLINE | ID: mdl-34995796
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur hormone gastrointestinale / Peptide gastrointestinal / Remodelage osseux / Glucagon-like peptide 2 / Récepteur du peptide-2 similaire au glucagon Type d'étude: Clinical_trials / Prognostic_studies Limites: Adult / Animals / Female / Humans / Male Langue: En Journal: Pharmacol Res Sujet du journal: FARMACOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Danemark Pays de publication: Pays-Bas
Texte intégral
Ajouter à My VHL
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XML
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur hormone gastrointestinale / Peptide gastrointestinal / Remodelage osseux / Glucagon-like peptide 2 / Récepteur du peptide-2 similaire au glucagon Type d'étude: Clinical_trials / Prognostic_studies Limites: Adult / Animals / Female / Humans / Male Langue: En Journal: Pharmacol Res Sujet du journal: FARMACOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Danemark Pays de publication: Pays-Bas