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Oligomerization, albumin binding and catabolism of therapeutic peptides in the subcutaneous compartment: An investigation on lipidated GLP-1 analogs.
Gallo, Mariana; Vanni, Domitilla; Esposito, Simone; Alaimo, Nadine; Orvieto, Federica; Rulli, Federica; Missineo, Antonino; Caretti, Fulvia; Bonelli, Fabio; Veneziano, Maria; Orsatti, Laura; Monteagudo, Edith.
Affiliation
  • Gallo M; Structural Biology and Computational Chemistry, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Vanni D; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy; Department of Chemical Science and Technology, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • Esposito S; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Alaimo N; Discovery Biology, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Orvieto F; Peptides and Small Molecules R&D Department, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Rulli F; Peptides and Small Molecules R&D Department, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Missineo A; Discovery Biology, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Caretti F; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Bonelli F; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Veneziano M; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Orsatti L; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy.
  • Monteagudo E; Drug Metabolism and Pharmacokinetics, IRBM SpA, Via Pontina Km 30 600, 00 071 Pomezia, Rome, Italy. Electronic address: edith.monteagudo@chdifoundation.org.
J Pharm Biomed Anal ; 210: 114566, 2022 Feb 20.
Article de En | MEDLINE | ID: mdl-35042144
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Diabète de type 2 / Glucagon-like peptide 1 Limites: Animals Langue: En Journal: J Pharm Biomed Anal Année: 2022 Type de document: Article Pays d'affiliation: Italie
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Diabète de type 2 / Glucagon-like peptide 1 Limites: Animals Langue: En Journal: J Pharm Biomed Anal Année: 2022 Type de document: Article Pays d'affiliation: Italie