Intratracheal administration of solutions in mice; development and validation of an optimized method with improved efficacy, reproducibility and accuracy.

Pelgrim, Charlotte E; van Ark, Ingrid; Leusink-Muis, Thea; Brans, Maike A D; Braber, Saskia; Garssen, Johan; van Helvoort, Ardy; Kraneveld, Aletta D; Folkerts, Gert

Pelgrim, Charlotte E; van Ark, Ingrid; Leusink-Muis, Thea; Brans, Maike A D; Braber, Saskia; Garssen, Johan; van Helvoort, Ardy; Kraneveld, Aletta D; Folkerts, Gert.

Affiliation

Pelgrim CE; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands. Electronic address: c.e.pelgrim@uu.nl.
van Ark I; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
Leusink-Muis T; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
Brans MAD; Experimental Cardiology, University Medical Center Utrecht, the Netherlands.
Braber S; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands; Platform Immunology, Danone Nutricia Research, Utrecht, the Netherlands.
van Helvoort A; Danone Nutricia Research, Utrecht, the Netherlands; NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Department of Respiratory Medicine, Maastricht, the Netherlands.
Kraneveld AD; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
Folkerts G; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands.

J Pharmacol Toxicol Methods ; 114: 107156, 2022.

Article de En | MEDLINE | ID: mdl-35085718

Sujet(s)
Mots clés

Instillation; Intratracheal; Intubation; Methods; Oropharyngeal

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plan de recherche / Intubation trachéale Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: J Pharmacol Toxicol Methods Sujet du journal: FARMACOLOGIA / TOXICOLOGIA Année: 2022 Type de document: Article Pays de publication: États-Unis d'Amérique

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