HER2 Mediates PSMA/mGluR1-Driven Resistance to the DS-7423 Dual PI3K/mTOR Inhibitor in PTEN Wild-type Prostate Cancer Models.

Gómez, Valentí; Galazi, Myria; Weitsman, Gregory; Monypenny, James; Al-Salemee, Fahad; Barber, Paul R; Ng, Kenrick; Beatson, Richard; Szokol, Bálint; Orfi, László; Mullen, Greg; Vanhaesebroeck, Bart; Chowdhury, Simon; Leung, Hing Y; Ng, Tony

Gómez, Valentí; Galazi, Myria; Weitsman, Gregory; Monypenny, James; Al-Salemee, Fahad; Barber, Paul R; Ng, Kenrick; Beatson, Richard; Szokol, Bálint; Orfi, László; Mullen, Greg; Vanhaesebroeck, Bart; Chowdhury, Simon; Leung, Hing Y; Ng, Tony.

Affiliation

Gómez V; UCL Cancer Institute, University College London, London, United Kingdom.
Galazi M; UCL Cancer Institute, University College London, London, United Kingdom.
Weitsman G; School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Monypenny J; School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Al-Salemee F; School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.
Barber PR; UCL Cancer Institute, University College London, London, United Kingdom.
Ng K; School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Beatson R; UCL Cancer Institute, University College London, London, United Kingdom.
Szokol B; School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
Orfi L; Vichem Chemie Ltd., Veszprém, Hungary.
Mullen G; Vichem Chemie Ltd., Veszprém, Hungary.
Vanhaesebroeck B; Department of Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary.
Chowdhury S; School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom.
Leung HY; UCL Cancer Institute, University College London, London, United Kingdom.
Ng T; Guy's, King's, and St. Thomas' Hospitals, and Sarah Cannon Research Institute, London, United Kingdom.

Mol Cancer Ther ; 21(4): 667-676, 2022 04 01.

Article de En | MEDLINE | ID: mdl-35086953

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs de la prostate / Phosphatidylinositol 3-kinases Limites: Humans / Male Langue: En Journal: Mol Cancer Ther Sujet du journal: ANTINEOPLASICOS Année: 2022 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: États-Unis d'Amérique

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