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INSPECT: A Retrospective Study to Evaluate Long-term Effectiveness and Safety of Darvadstrocel in Patients With Perianal Fistulizing Crohn's Disease Treated in the ADMIRE-CD Trial.
Panés, Julian; Bouma, Gerd; Ferrante, Marc; Kucharzik, Torsten; Nachury, Maria; de la Portilla de Juan, Fernando; Reinisch, Walter; Selvaggi, Francesco; Tschmelitsch, Jörg; Brett, Neil R; Ladouceur, Martin; Binek, Matthias; Hantsbarger, Gary; Campbell-Hill, Sarah; Karki, Chitra; Buskens, Christianne.
Affiliation
  • Panés J; Inflammatory Bowel Disease Unit, Hospital Clínic de Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
  • Bouma G; Amsterdam Gastroenterology Endocrinology and Metabolism, Department of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, the Netherlands.
  • Ferrante M; Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
  • Kucharzik T; Department of Internal Medicine and Gastroenterology, University Teaching Hospital Lüneburg, University of Hamburg, Lüneburg, Germany.
  • Nachury M; U1286 - INFINITE - Institute for Translational Research in Inflammation, Centre Hospitalier Universitaire de Lille, University of Lille, Lille, France.
  • de la Portilla de Juan F; Departamento de Cirugia, Hospital Universitario Virgen del Rocío, University of Seville, Seville, Spain.
  • Reinisch W; Department for Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
  • Selvaggi F; Division of Gastroenterology, McMaster University, Hamilton, ON, Canada.
  • Tschmelitsch J; Unit of Colorectal Surgery, Department of Medical, Surgical, Neurological, Metabolic and Ageing Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
  • Brett NR; Department of Surgery, Hospital Barmherzige Brüder, Sankt Veit an der Glan, Austria.
  • Ladouceur M; Evidera, Montréal, QC, Canada.
  • Binek M; Evidera, Montréal, QC, Canada.
  • Hantsbarger G; Takeda Pharmaceuticals International AG, Zurich, Switzerland.
  • Campbell-Hill S; Takeda Pharmaceutical Company Limited, Cambridge, MA, USA.
  • Karki C; Takeda UK Ltd, London, United Kingdom.
  • Buskens C; Takeda Pharmaceutical Company Limited, Cambridge, MA, USA.
Inflamm Bowel Dis ; 28(11): 1737-1745, 2022 11 02.
Article de En | MEDLINE | ID: mdl-35099555
This retrospective chart review of patients treated with darvadstrocel indicates sustained remission and confirms a favorable safety profile up to 156 weeks after a single administration of stem cells for treatment of complex perianal fistulas in patients with Crohn's disease.
Sujet(s)
Mots clés

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladie de Crohn / Fistule rectale / Fistule cutanée / Transplantation de cellules souches mésenchymateuses Type d'étude: Etiology_studies / Observational_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Inflamm Bowel Dis Sujet du journal: GASTROENTEROLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Espagne Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladie de Crohn / Fistule rectale / Fistule cutanée / Transplantation de cellules souches mésenchymateuses Type d'étude: Etiology_studies / Observational_studies / Risk_factors_studies Limites: Humans Langue: En Journal: Inflamm Bowel Dis Sujet du journal: GASTROENTEROLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Espagne Pays de publication: Royaume-Uni