Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach.

Smith, Kyle P; Lee, Woonghee; Tonelli, Marco; Lee, Yeongjoon; Light, Samuel H; Cornilescu, Gabriel; Chakravarthy, Srinivas

Smith, Kyle P; Lee, Woonghee; Tonelli, Marco; Lee, Yeongjoon; Light, Samuel H; Cornilescu, Gabriel; Chakravarthy, Srinivas.

Affiliation

Smith KP; Department of Cell & Developmental Biology, Northwestern University Chicago, Illinois, USA.
Lee W; Xilio Therapeutics, Waltham, Massachusetts, USA.
Tonelli M; Department of Chemistry, University of Colorado-Denver, Denver, Colorado, USA.
Lee Y; National Magnetic Resonance Facility at Madison, Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Light SH; Department of Chemistry, University of Colorado-Denver, Denver, Colorado, USA.
Cornilescu G; Department of Microbiology, University of Chicago, Chicago, Illinois, USA.
Chakravarthy S; Advanced Technology Research Facility, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.

Protein Sci ; 31(5): e4282, 2022 05.

Article de En | MEDLINE | ID: mdl-35137487

Sujet(s)
Mots clés

ExoS; GTP hydrolysis; T3SS secretion system; Vibrio Cholerae; YopE; catalytic arginine finger; helical bundle; mitochondrial dynamics; relaxation dispersion; small-angle x-ray scattering

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Vibrio / Protéines d'activation de la GTPase Type d'étude: Prognostic_studies Langue: En Journal: Protein Sci Sujet du journal: BIOQUIMICA Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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