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Drug repurposing through virtual screening and in vitro validation identifies tigecycline as a novel putative HCV polymerase inhibitor.
ElHefnawi, Mahmoud; Jo, Eunji; Tolba, Mahmoud M; Fares, Mohamed; Yang, Jaewon; Shahbaaz, Mohd; Windisch, Marc P.
Affiliation
  • ElHefnawi M; Biomedical Informatics and Chemoinformatics Group, Informatics and Systems Department, National Research Centre, Cairo, Egypt.
  • Jo E; Applied Molecular Virology Laboratory, Discovery Biology Division, Institut Pasteur Korea, Sampyung-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Tolba MM; Biomedical Informatics and Chemoinformatics Group, Informatics and Systems Department, National Research Centre, Cairo, Egypt.
  • Fares M; Biomedical Informatics and Chemoinformatics Group, Informatics and Systems Department, National Research Centre, Cairo, Egypt; Center for Informatics Science (CIS), Nile University, Juhayna Square, Sheikh Zayed City, Giza, Egypt.
  • Yang J; Applied Molecular Virology Laboratory, Discovery Biology Division, Institut Pasteur Korea, Sampyung-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea.
  • Shahbaaz M; South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, South Africa; Laboratory of Computational Modeling of Drugs, South Ural State University, Chelyabinsk, Russia.
  • Windisch MP; Applied Molecular Virology Laboratory, Discovery Biology Division, Institut Pasteur Korea, Sampyung-dong, Bundang-gu, Seongnam-si, Gyeonggi-do, South Korea; Division of Bio-Medical Science and Technology, University of Science and Technology, Yuseong-gu, Daejeon, South Korea. Electronic address: mar
Virology ; 570: 9-17, 2022 05.
Article de En | MEDLINE | ID: mdl-35338891
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite C / Hepacivirus Type d'étude: Diagnostic_studies / Screening_studies Limites: Humans Langue: En Journal: Virology Année: 2022 Type de document: Article Pays d'affiliation: Égypte
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite C / Hepacivirus Type d'étude: Diagnostic_studies / Screening_studies Limites: Humans Langue: En Journal: Virology Année: 2022 Type de document: Article Pays d'affiliation: Égypte