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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer.
Peuker, Kenneth; Strigli, Anne; Tauriello, Daniele V F; Hendricks, Alexander; von Schönfels, Witigo; Burmeister, Greta; Brosch, Mario; Herrmann, Alexander; Krüger, Sandra; Nitsche, Jessica; Juznic, Lea; Geissler, Marc Marius; Hiergeist, Andreas; Gessner, André; Wirbel, Jakob; Ponnudurai, Ruby Priyadarshini; Tunger, Antje; Wehner, Rebekka; Stange, Daniel E; Weitz, Jürgen; Aust, Daniela E; Baretton, Gustavo B; Schmitz, Marc; Röcken, Christoph; Hampe, Jochen; Hinz, Sebastian; Zeller, Georg; Chavakis, Triantafyllos; Schafmayer, Clemens; Batlle, Eduard; Zeissig, Sebastian.
Affiliation
  • Peuker K; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Strigli A; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Tauriello DVF; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri i Reixac 10, 08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 08028 Barcelona, Spain.
  • Hendricks A; Department of General and Thoracic Surgery, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany; Department of General Surgery, University Medicine Rostock, 18507 Rostock, Germany.
  • von Schönfels W; Department of General and Thoracic Surgery, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
  • Burmeister G; Department of General and Thoracic Surgery, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany; Department of General Surgery, University Medicine Rostock, 18507 Rostock, Germany.
  • Brosch M; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Herrmann A; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Krüger S; Institute of Pathology, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
  • Nitsche J; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Juznic L; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Geissler MM; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Hiergeist A; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, 93042 Regensburg, Germany.
  • Gessner A; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, 93042 Regensburg, Germany.
  • Wirbel J; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
  • Ponnudurai RP; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
  • Tunger A; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany.
  • Wehner R; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany.
  • Stange DE; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, 01307 Dresden, Germany; German Cancer Consortium (DKTK), Partner Site
  • Weitz J; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany; Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, 01307 Dresden, Germany; German Cancer Consortium (DKTK), Partner Site
  • Aust DE; Institute of Pathology, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany; Tumor and Normal Tissue Bank of the University Cancer Center (UCC), University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany.
  • Baretton GB; Institute of Pathology, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany.
  • Schmitz M; Institute of Immunology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany; National Center for Tumor Diseases (NCT), Partner Site Dresden, 01307 Dresden, Germany; German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany; German Cancer Resea
  • Röcken C; Institute of Pathology, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany.
  • Hampe J; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Hinz S; Department of General and Thoracic Surgery, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany; Department of General Surgery, University Medicine Rostock, 18507 Rostock, Germany.
  • Zeller G; Structural and Computational Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.
  • Chavakis T; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany.
  • Schafmayer C; Department of General and Thoracic Surgery, University Medical Center Schleswig-Holstein, 24105 Kiel, Germany; Department of General Surgery, University Medicine Rostock, 18507 Rostock, Germany.
  • Batlle E; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri i Reixac 10, 08028 Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), 08028 Barcelona, Spain; ICREA, Pg. Lluís Companys 23, 08010 Barcelona, Spain.
  • Zeissig S; Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany. Electronic address: sebastian.zeissig@tu-dresden.de.
Immunity ; 55(4): 701-717.e7, 2022 04 12.
Article de En | MEDLINE | ID: mdl-35364006
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs colorectales / Microbiote Limites: Animals Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
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XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs colorectales / Microbiote Limites: Animals Langue: En Journal: Immunity Sujet du journal: ALERGIA E IMUNOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique