Photocatalytic Markovnikov-type addition and cyclization of terminal alkynes leading to 4-sulfonyl quinoline-2(1H)-ones.
Chem Commun (Camb)
; 58(33): 5112-5115, 2022 Apr 21.
Article
de En
| MEDLINE
| ID: mdl-35377376
ABSTRACT
A new and expedient photocatalytic protocol for the construction of quinolin-2(1H)-ones via Markovnikov-type sulfonylation/6-endo-trig cyclization/selective C(O)-CF3 bond cleavage starting from N-alkyl-N-(2-ethynylphenyl)-2,2,2-trifluoroacetamides and sulfinic acids has been developed. It is as an unprecedented protocol for the preparation of 4-sulfonylquinoline-2(1H)-ones with high efficiency, mild reaction conditions, acceptable yields and a wide range of substrates.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Quinoléines
/
Alcynes
Langue:
En
Journal:
Chem Commun (Camb)
Sujet du journal:
QUIMICA
Année:
2022
Type de document:
Article