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Design, synthesis and properties of hydrogen peroxide fluorescent probe based on benzothiazole.
Ma, Tao; Zhang, Ye; Fu, Kai; Li, Zhichun; Yuan, Changchun; Ma, Wenbing.
Affiliation
  • Ma T; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China.
  • Zhang Y; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China.
  • Fu K; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China.
  • Li Z; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China.
  • Yuan C; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China. Electronic address: ycc543700483@nuc.edu.cn.
  • Ma W; School of Chemical Engineering and Technology, North University of China,Taiyuan 030051, PR China. Electronic address: mawenbing@nuc.edu.cn.
Bioorg Chem ; 123: 105798, 2022 06.
Article de En | MEDLINE | ID: mdl-35413581
ABSTRACT
Abnormal intracellular hydrogen peroxide (H2O2) concentration is related to cancer, cardiovascular, cerebrovascular diseases and other diseases. A novel H2O2 fluorescent probe (BBS) was designed and synthesized. The fluorescence intensity shows good linear relationship with the concentration of H2O2 (0-40 µM), and the detection limit is 132 nM. The response mechanism of probe BBS was verified and analyzed by UV-Vis spectra, titration spectra and density functional theory (DFT) on Gaussian 09 programme. BBS can be used for bioimaging in living cells.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Colorants fluorescents / Peroxyde d'hydrogène Limites: Humans Langue: En Journal: Bioorg Chem Année: 2022 Type de document: Article
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Colorants fluorescents / Peroxyde d'hydrogène Limites: Humans Langue: En Journal: Bioorg Chem Année: 2022 Type de document: Article