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Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection.
Kenney, Devin J; O'Connell, Aoife K; Turcinovic, Jacquelyn; Montanaro, Paige; Hekman, Ryan M; Tamura, Tomokazu; Berneshawi, Andrew R; Cafiero, Thomas R; Al Abdullatif, Salam; Blum, Benjamin; Goldstein, Stanley I; Heller, Brigitte L; Gertje, Hans P; Bullitt, Esther; Trachtenberg, Alexander J; Chavez, Elizabeth; Nono, Evans Tuekam; Morrison, Catherine; Tseng, Anna E; Sheikh, Amira; Kurnick, Susanna; Grosz, Kyle; Bosmann, Markus; Ericsson, Maria; Huber, Bertrand R; Saeed, Mohsan; Balazs, Alejandro B; Francis, Kevin P; Klose, Alexander; Paragas, Neal; Campbell, Joshua D; Connor, John H; Emili, Andrew; Crossland, Nicholas A; Ploss, Alexander; Douam, Florian.
Affiliation
  • Kenney DJ; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • O'Connell AK; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Turcinovic J; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Bioinformatics Program, Boston University, Boston, MA, USA.
  • Montanaro P; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Hekman RM; Center for Network Systems Biology, Boston University, Boston, MA, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.
  • Tamura T; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Berneshawi AR; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Cafiero TR; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Al Abdullatif S; Single Cell RNA Sequencing Core, Boston University, Boston, MA, USA; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Blum B; Center for Network Systems Biology, Boston University, Boston, MA, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.
  • Goldstein SI; Center for Network Systems Biology, Boston University, Boston, MA, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.
  • Heller BL; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
  • Gertje HP; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Bullitt E; Department of Physiology and Biophysics, Boston University School of Medicine, Boston, MA, USA.
  • Trachtenberg AJ; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Chavez E; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Nono ET; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Morrison C; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Tseng AE; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Sheikh A; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Kurnick S; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Animal Science Center, Boston University, Boston, MA, USA.
  • Grosz K; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Animal Science Center, Boston University, Boston, MA, USA.
  • Bosmann M; Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz 55131, Germany.
  • Ericsson M; Electron Microscopy Core Facility, Harvard Medical School, Boston, MA, USA.
  • Huber BR; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
  • Saeed M; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA.
  • Balazs AB; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Francis KP; PerkinElmer, Hopkinton, MA, USA.
  • Klose A; In Vivo Analytics, Inc., New York, NY, USA.
  • Paragas N; In Vivo Analytics, Inc., New York, NY, USA; Department of Radiology Imaging Research Lab, University of Washington, Seattle, WA, USA.
  • Campbell JD; Single Cell RNA Sequencing Core, Boston University, Boston, MA, USA; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Connor JH; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
  • Emili A; Center for Network Systems Biology, Boston University, Boston, MA, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, USA; Department of Biology, Boston University School of Medicine, Boston, MA, USA.
  • Crossland NA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA. Electronic address: ncrossla@bu.edu.
  • Ploss A; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. Electronic address: aploss@princeton.edu.
  • Douam F; Department of Microbiology, Boston University School of Medicine, Boston, MA, USA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA. Electronic address: fdouam@bu.edu.
Cell Rep ; 39(3): 110714, 2022 04 19.
Article de En | MEDLINE | ID: mdl-35421379

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: COVID-19 Limites: Animals / Humans Langue: En Journal: Cell Rep Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: COVID-19 Limites: Animals / Humans Langue: En Journal: Cell Rep Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique