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Therapeutic targeting of STING-TBK1-IRF3 signalling ameliorates chronic stress induced depression-like behaviours by modulating neuroinflammation and microglia phagocytosis.
Duan, Na; Zhang, Yanpeng; Tan, Shuwen; Sun, Jianyu; Ye, Mao; Gao, Hui; Pu, Kairui; Wu, Meiyan; Wang, Qiang; Zhai, Qian.
Affiliation
  • Duan N; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Zhang Y; Department of Thoracic Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Tan S; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Sun J; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Ye M; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Gao H; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Pu K; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Wu M; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China.
  • Wang Q; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China. Electronic address: dr.wangqiang@139.com.
  • Zhai Q; Department of Anesthesiology and Center for Brain Science, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, Shaanxi, China. Electronic address: zhaiqian312@163.com.
Neurobiol Dis ; 169: 105739, 2022 07.
Article de En | MEDLINE | ID: mdl-35470042
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Microglie / Facteur-3 de régulation d'interféron Type d'étude: Etiology_studies Limites: Animals Langue: En Journal: Neurobiol Dis Sujet du journal: NEUROLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Microglie / Facteur-3 de régulation d'interféron Type d'étude: Etiology_studies Limites: Animals Langue: En Journal: Neurobiol Dis Sujet du journal: NEUROLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Chine Pays de publication: États-Unis d'Amérique