Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors.

Parkhurst, Ashlyn; Wang, Sabrina Z; Findlay, Tyler R; Malebranche, Kristen J; Odabas, Arman; Alt, Jesse; Maxwell, Micah J; Kaur, Harpreet; Peer, Cody J; Figg, William D; Warren, Katherine E; Slusher, Barbara S; Eberhart, Charles G; Raabe, Eric H; Rubens, Jeffrey A

Parkhurst, Ashlyn; Wang, Sabrina Z; Findlay, Tyler R; Malebranche, Kristen J; Odabas, Arman; Alt, Jesse; Maxwell, Micah J; Kaur, Harpreet; Peer, Cody J; Figg, William D; Warren, Katherine E; Slusher, Barbara S; Eberhart, Charles G; Raabe, Eric H; Rubens, Jeffrey A.

Affiliation

Parkhurst A; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Wang SZ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Findlay TR; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Malebranche KJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Odabas A; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Alt J; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Maxwell MJ; Division of Cell Biology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Kaur H; Clinical Pharmacology Program, National Cancer Institute at the National Institutes of Health, 37 Convent Dr, Bethesda, MD, 20892, USA.
Peer CJ; Johns Hopkins Drug Discovery, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Figg WD; Department of Neurology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Warren KE; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Slusher BS; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Eberhart CG; Division of Pediatric Oncology, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Raabe EH; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, 1800 Orleans St, Baltimore, MD, 21287, USA.
Rubens JA; Clinical Pharmacology Program, National Cancer Institute at the National Institutes of Health, 37 Convent Dr, Bethesda, MD, 20892, USA.

Cell Death Dis ; 13(4): 410, 2022 04 28.

Article de En | MEDLINE | ID: mdl-35484114

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeur rhabdoïde Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Cell Death Dis Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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