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Pevonedistat in East Asian patients with acute myeloid leukemia or myelodysplastic syndromes: a phase 1/1b study to evaluate safety, pharmacokinetics and activity as a single agent and in combination with azacitidine.
Handa, Hiroshi; Cheong, June-Won; Onishi, Yasushi; Iida, Hiroatsu; Kobayashi, Yukio; Kim, Hyeoung-Joon; Chiou, Tzeon-Jye; Izutsu, Koji; Tsukurov, Olga; Zhou, Xiaofei; Faessel, Helene; Yuan, Ying; Sedarati, Farhad; Faller, Douglas V; Kimura, Akiko; Wu, Shang-Ju.
Affiliation
  • Handa H; National University Corporation, Gunma University, Maebashi, Japan.
  • Cheong JW; Severence Hospital, Yonsei University Health System, Seoul, South Korea.
  • Onishi Y; National University, Corporation Tohoku University, Sendai, Japan.
  • Iida H; National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
  • Kobayashi Y; International University of Health and Welfare, Mita Hospital, Tokyo, Japan.
  • Kim HJ; Chonnam National University, Hwasun Hospital, Hwasun, South Korea.
  • Chiou TJ; Taipei Municipal Wanfang Hospital, Taipei Medical University, Taipei Veterans General Hospital, Taipei, Taiwan.
  • Izutsu K; National Cancer Center Hospital, Tokyo, Japan.
  • Tsukurov O; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Zhou X; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Faessel H; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Yuan Y; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Sedarati F; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Faller DV; Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA.
  • Kimura A; Takeda Pharmaceutical Company Limited, Osaka, Japan.
  • Wu SJ; Division of Hematology, Department of Internal Medicine, Zhongzheng Dist, National Taiwan University Hospital, No.7, Zhongshan S. Rd., Taipei City, 100, Taiwan. wushangju@ntu.edu.tw.
J Hematol Oncol ; 15(1): 56, 2022 05 11.
Article de En | MEDLINE | ID: mdl-35545778
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyrimidines / Syndromes myélodysplasiques / Leucémie aigüe myéloïde / Cyclopentanes Limites: Adult / Humans Langue: En Journal: J Hematol Oncol Sujet du journal: HEMATOLOGIA / NEOPLASIAS Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyrimidines / Syndromes myélodysplasiques / Leucémie aigüe myéloïde / Cyclopentanes Limites: Adult / Humans Langue: En Journal: J Hematol Oncol Sujet du journal: HEMATOLOGIA / NEOPLASIAS Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: Royaume-Uni