Humanised Mice and Immunodeficient Mice (NSG) Are Equally Sensitive for Prediction of Stem Cell Malignancy in the Teratoma Assay.

Bialecka, Monika; Montilla-Rojo, Joaquin; Roelen, Bernard A J; Gillis, Ad J; Looijenga, Leendert H J; Salvatori, Daniela C F

Bialecka, Monika; Montilla-Rojo, Joaquin; Roelen, Bernard A J; Gillis, Ad J; Looijenga, Leendert H J; Salvatori, Daniela C F.

Affiliation

Bialecka M; Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.
Montilla-Rojo J; Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.
Roelen BAJ; Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.
Gillis AJ; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Looijenga LHJ; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, The Netherlands.
Salvatori DCF; Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

Int J Mol Sci ; 23(9)2022 Apr 23.

Article de En | MEDLINE | ID: mdl-35563071

Sujet(s)
Mots clés

hPSCs; hiPSCs; humanised mice; malignancy; pluripotency; teratoma assay

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tératome / Cellules souches pluripotentes Type d'étude: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limites: Animals / Humans Langue: En Journal: Int J Mol Sci Année: 2022 Type de document: Article Pays d'affiliation: Pays-Bas Pays de publication: Suisse

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