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Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.
Zhu, Keying; Wang, Yang; Sarlus, Heela; Geng, Keyi; Nutma, Erik; Sun, Jingxian; Kung, Shin-Yu; Bay, Cindy; Han, Jinming; Min, Jin-Hong; Benito-Cuesta, Irene; Lund, Harald; Amor, Sandra; Wang, Jun; Zhang, Xing-Mei; Kutter, Claudia; Guerreiro-Cacais, André Ortlieb; Högberg, Björn; Harris, Robert A.
Affiliation
  • Zhu K; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Wang Y; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Sarlus H; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Geng K; Department of Microbiology, Tumor and Cell Biology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden.
  • Nutma E; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands.
  • Sun J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.
  • Kung SY; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.
  • Bay C; Shanghai Medical College, Fudan University, Shanghai, China.
  • Han J; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Min JH; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Benito-Cuesta I; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Lund H; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Amor S; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Wang J; Department of Physiology and Pharmacology, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
  • Zhang XM; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands.
  • Kutter C; Department of Integrative Medicine and Neurobiology, School of Basic Medical Sciences, Shanghai, China.
  • Guerreiro-Cacais AO; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Shanghai, China.
  • Högberg B; Shanghai Medical College, Fudan University, Shanghai, China.
  • Harris RA; Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
EMBO Rep ; 23(7): e54499, 2022 07 05.
Article de En | MEDLINE | ID: mdl-35593064

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Inhibiteurs de la topoisomérase-I / Maladies neuro-inflammatoires Limites: Animals Langue: En Journal: EMBO Rep Sujet du journal: BIOLOGIA MOLECULAR Année: 2022 Type de document: Article Pays d'affiliation: Suède

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Inhibiteurs de la topoisomérase-I / Maladies neuro-inflammatoires Limites: Animals Langue: En Journal: EMBO Rep Sujet du journal: BIOLOGIA MOLECULAR Année: 2022 Type de document: Article Pays d'affiliation: Suède