NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial-mesenchymal transition.

Min, Li; Shu-Li, Zhang; Feng, Yuan; Han, Hu; Shao-Jun, Li; Sheng-Xiong, Tong; Jia-Yu, Tian; Xiang-Zhi, Fang; Dan, Feng

Min, Li; Shu-Li, Zhang; Feng, Yuan; Han, Hu; Shao-Jun, Li; Sheng-Xiong, Tong; Jia-Yu, Tian; Xiang-Zhi, Fang; Dan, Feng.

Affiliation

Min L; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Shu-Li Z; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Feng Y; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Han H; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Shao-Jun L; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Sheng-Xiong T; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Jia-Yu T; Department of Pain Management, Wuhan First Hospital, Wuhan, China.
Xiang-Zhi F; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Dan F; Department of Pain Management, Wuhan First Hospital, Wuhan, China. fengdan_pain@126.com.

Respir Res ; 23(1): 128, 2022 May 20.

Article de En | MEDLINE | ID: mdl-35596212

Sujet(s)
Mots clés

EMT; Fibrosis; Lung injury; NLRP3; NecroX-5

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Fibrose pulmonaire / Sulfones / Transition épithélio-mésenchymateuse / Protéine-3 de la famille des NLR contenant un domaine pyrine / Composés hétérocycliques avec 4 noyaux ou plus Limites: Animals Langue: En Journal: Respir Res Année: 2022 Type de document: Article Pays d'affiliation: Chine

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