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Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.
Mätlik, Kärt; Garton, Daniel R; Montaño-Rodríguez, Ana R; Olfat, Soophie; Eren, Feride; Casserly, Laoise; Damdimopoulos, Anastasios; Panhelainen, Anne; Porokuokka, L Lauriina; Kopra, Jaakko J; Turconi, Giorgio; Schweizer, Nadine; Bereczki, Erika; Piehl, Fredrik; Engberg, Göran; Cervenka, Simon; Piepponen, T Petteri; Zhang, Fu-Ping; Sipilä, Petra; Jakobsson, Johan; Sellgren, Carl M; Erhardt, Sophie; Andressoo, Jaan-Olle.
Affiliation
  • Mätlik K; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland. kmatlik01@rockefeller.edu.
  • Garton DR; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Montaño-Rodríguez AR; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Olfat S; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Eren F; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, 14183, Huddinge, Sweden.
  • Casserly L; Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
  • Damdimopoulos A; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Panhelainen A; Department of Biosciences and Nutrition, Karolinska Institutet, 14183, Huddinge, Sweden.
  • Porokuokka LL; Institute of Biotechnology, University of Helsinki, 00014, Helsinki, Finland.
  • Kopra JJ; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Turconi G; Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, 00014, Helsinki, Finland.
  • Schweizer N; Department of Pharmacology, Faculty of Medicine, Neuroscience Center & Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Bereczki E; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, 14183, Huddinge, Sweden.
  • Piehl F; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, 14183, Huddinge, Sweden.
  • Engberg G; Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Karolinska University Hospital, 17177, Stockholm, Sweden.
  • Cervenka S; Department of Physiology and Pharmacology, Karolinska Institutet, 17177, Stockholm, Sweden.
  • Piepponen TP; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Region Stockholm, 17177, Stockholm, Sweden.
  • Zhang FP; Department of Medical Sciences, Psychiatry, Uppsala University, 75185, Uppsala, Sweden.
  • Sipilä P; Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, 00014, Helsinki, Finland.
  • Jakobsson J; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine and Turku Center for Disease Modeling, University of Turku, 20520, Turku, Finland.
  • Sellgren CM; GM-Unit, Laboratory Animal Center, Helsinki Institute of Life Science, University of Helsinki, 00290, Helsinki, Finland.
  • Erhardt S; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine and Turku Center for Disease Modeling, University of Turku, 20520, Turku, Finland.
  • Andressoo JO; Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, BMC A11, Lund University, 221 84, Lund, Sweden.
Mol Psychiatry ; 27(8): 3247-3261, 2022 08.
Article de En | MEDLINE | ID: mdl-35618883

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizophrénie / Dopamine Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Mol Psychiatry Sujet du journal: BIOLOGIA MOLECULAR / PSIQUIATRIA Année: 2022 Type de document: Article Pays d'affiliation: Finlande

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Schizophrénie / Dopamine Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Mol Psychiatry Sujet du journal: BIOLOGIA MOLECULAR / PSIQUIATRIA Année: 2022 Type de document: Article Pays d'affiliation: Finlande