The Clinical and Genomic Epidemiology of Rhinovirus in Homeless Shelters-King County, Washington.
J Infect Dis
; 226(Suppl 3): S304-S314, 2022 10 07.
Article
de En
| MEDLINE
| ID: mdl-35749582
ABSTRACT
BACKGROUND:
Rhinovirus (RV) is a common cause of respiratory illness in all people, including those experiencing homelessness. RV epidemiology in homeless shelters is unknown.METHODS:
We analyzed data from a cross-sectional homeless shelter study in King County, Washington, October 2019-May 2021. Shelter residents or guardians aged ≥3 months reporting acute respiratory illness completed questionnaires and submitted nasal swabs. After 1 April 2020, enrollment expanded to residents and staff regardless of symptoms. Samples were tested by multiplex RT-PCR for respiratory viruses. A subset of RV-positive samples was sequenced.RESULTS:
There were 1066 RV-positive samples with RV present every month of the study period. RV was the most common virus before and during the coronavirus disease 2019 (COVID-19) pandemic (43% and 77% of virus-positive samples, respectively). Participants from family shelters had the highest prevalence of RV. Among 131 sequenced samples, 33 RV serotypes were identified with each serotype detected for ≤4 months.CONCLUSIONS:
RV infections persisted through community mitigation measures and were most prevalent in shelters housing families. Sequencing showed a diversity of circulating RV serotypes, each detected over short periods of time. Community-based surveillance in congregate settings is important to characterize respiratory viral infections during and after the COVID-19 pandemic. CLINICAL TRIALS REGISTRATION NCT04141917.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Virus
/
/
Infections à entérovirus
/
COVID-19
Type d'étude:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Screening_studies
Aspects:
Determinantes_sociais_saude
Limites:
Humans
Pays/Région comme sujet:
America do norte
Langue:
En
Journal:
J Infect Dis
Année:
2022
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique