Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.

Barnes, Ryan P; de Rosa, Mariarosaria; Thosar, Sanjana A; Detwiler, Ariana C; Roginskaya, Vera; Van Houten, Bennett; Bruchez, Marcel P; Stewart-Ornstein, Jacob; Opresko, Patricia L

Barnes, Ryan P; de Rosa, Mariarosaria; Thosar, Sanjana A; Detwiler, Ariana C; Roginskaya, Vera; Van Houten, Bennett; Bruchez, Marcel P; Stewart-Ornstein, Jacob; Opresko, Patricia L.

Affiliation

Barnes RP; Department of Environmental and Occupational Health, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
de Rosa M; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Thosar SA; Department of Environmental and Occupational Health, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
Detwiler AC; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Roginskaya V; Department of Environmental and Occupational Health, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
Van Houten B; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Bruchez MP; Department of Environmental and Occupational Health, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.
Stewart-Ornstein J; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Opresko PL; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.

Nat Struct Mol Biol ; 29(7): 639-652, 2022 07.

Article de En | MEDLINE | ID: mdl-35773409

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Raccourcissement des télomères / Guanine Limites: Humans Langue: En Journal: Nat Struct Mol Biol Sujet du journal: BIOLOGIA MOLECULAR Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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