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Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation.
Matsui, Yasuzumi; Mineharu, Yohei; Noguchi, Yuki; Hattori, Etsuko Yamamoto; Kubota, Hirohito; Hirata, Masahiro; Miyamoto, Susumu; Sugiyama, Hiroshi; Arakawa, Yoshiki; Kamikubo, Yasuhiko.
Affiliation
  • Matsui Y; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Mineharu Y; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan; Department of Artificial Intelligence in Healthcare and Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Noguchi Y; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Hattori EY; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Kubota H; Department of Pediatrics, Graduate School of Medicine, Kyoto University, 606-8507, Kyoto, Japan.
  • Hirata M; Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto City, Kyoto, 606-8507, Japan.
  • Miyamoto S; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan.
  • Sugiyama H; Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, 606-8502, Japan. Electronic address: hs@kuchem.kyoto-u.ac.jp.
  • Arakawa Y; Department of Neurosurgery, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan. Electronic address: yarakawa@kuhp.kyoto-u.ac.jp.
  • Kamikubo Y; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507, Japan. Electronic address: kamikubo.yasuhiko.7u@kyoto-u.ac.jp.
Biochem Biophys Res Commun ; 620: 150-157, 2022 09 10.
Article de En | MEDLINE | ID: mdl-35792512
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du cervelet / Médulloblastome Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Biochem Biophys Res Commun Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du cervelet / Médulloblastome Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Biochem Biophys Res Commun Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique