Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade.

Hooper, Andrea T; Marquette, Kimberly; Chang, Chao-Pei Betty; Golas, Jonathon; Jain, Sadhana; Lam, My-Hanh; Guffroy, Magali; Leal, Mauricio; Falahatpisheh, Hadi; Mathur, Divya; Chen, Ting; Kelleher, Kerry; Khandke, Kiran; Muszynska, Elwira; Loganzo, Frank; Rosfjord, Edward; Lucas, Judy; Kan, Zhengyan; Subramanyam, Chakrapani; O'Donnell, Christopher; Neri, Dario; Gerber, Hans-Peter; May, Chad; Sapra, Puja

Hooper, Andrea T; Marquette, Kimberly; Chang, Chao-Pei Betty; Golas, Jonathon; Jain, Sadhana; Lam, My-Hanh; Guffroy, Magali; Leal, Mauricio; Falahatpisheh, Hadi; Mathur, Divya; Chen, Ting; Kelleher, Kerry; Khandke, Kiran; Muszynska, Elwira; Loganzo, Frank; Rosfjord, Edward; Lucas, Judy; Kan, Zhengyan; Subramanyam, Chakrapani; O'Donnell, Christopher; Neri, Dario; Gerber, Hans-Peter; May, Chad; Sapra, Puja.

Affiliation

Hooper AT; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Marquette K; Pfizer Worldwide Research, Development & Medicine, BioMedicine Design, Cambridge, Massachusetts.
Chang CB; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Golas J; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Jain S; Pfizer Worldwide Research, Development & Medicine, BioMedicine Design, Cambridge, Massachusetts.
Lam MH; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Guffroy M; Pfizer Worldwide Research, Development & Medicine, Drug Safety Research & Development, Pearl River, New York.
Leal M; Pfizer Worldwide Research, Development & Medicine, BioMedicine Design, Cambridge, Massachusetts.
Falahatpisheh H; Pfizer Worldwide Research, Development & Medicine, Drug Safety Research & Development, Pearl River, New York.
Mathur D; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Chen T; Pfizer Worldwide Research, Development & Medicine, BioMedicine Design, Cambridge, Massachusetts.
Kelleher K; Pfizer Worldwide Research, Development & Medicine, BioMedicine Design, Cambridge, Massachusetts.
Khandke K; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Muszynska E; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Loganzo F; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Rosfjord E; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Lucas J; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Kan Z; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Subramanyam C; Pfizer Worldwide Medicinal Chemistry, Groton, Connecticut.
O'Donnell C; Pfizer Worldwide Medicinal Chemistry, Groton, Connecticut.
Neri D; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.
Gerber HP; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
May C; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.
Sapra P; Pfizer Worldwide Research, Development & Medicine, Oncology Research & Development, Pearl River, New York.

Mol Cancer Ther ; 21(9): 1462-1472, 2022 09 06.

Article de En | MEDLINE | ID: mdl-35793468

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du sein / Immunoconjugués Limites: Animals / Female / Humans Langue: En Journal: Mol Cancer Ther Sujet du journal: ANTINEOPLASICOS Année: 2022 Type de document: Article

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