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Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB.
Yuen, Man-Fung; Locarnini, Stephen; Lim, Tien Huey; Strasser, Simone I; Sievert, William; Cheng, Wendy; Thompson, Alex J; Given, Bruce D; Schluep, Thomas; Hamilton, James; Biermer, Michael; Kalmeijer, Ronald; Beumont, Maria; Lenz, Oliver; De Ridder, Filip; Cloherty, Gavin; Ka-Ho Wong, Danny; Schwabe, Christian; Jackson, Kathy; Lai, Ching Lung; Gish, Robert G; Gane, Edward.
Affiliation
  • Yuen MF; Department of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: mfyuen@hku.hk.
  • Locarnini S; Victorian Infectious Diseases Reference Laboratory, Victoria, Australia.
  • Lim TH; Department of Gastroenterology, Middlemore Hospital, Auckland, New Zealand.
  • Strasser SI; AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia.
  • Sievert W; Department of Gastroenterology, Monash Health and Monash University, Melbourne, Australia.
  • Cheng W; Department of Gastroenterology and Hepatology, Royal Perth Hospital, Perth, Australia; Linear Clinical Research, Perth, Australia.
  • Thompson AJ; Department of Gastroenterology, St. Vincent's Hospital, Melbourne, Australia.
  • Given BD; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Schluep T; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Hamilton J; Arrowhead Pharmaceuticals, Pasadena, CA, USA.
  • Biermer M; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Kalmeijer R; Janssen Research & Development, Titusville, NJ, USA.
  • Beumont M; Janssen Research & Development, Titusville, NJ, USA.
  • Lenz O; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • De Ridder F; Janssen Pharmaceuticals NV, Beerse, Belgium.
  • Cloherty G; Abbott Diagnostics, Abbott Park, IL, USA.
  • Ka-Ho Wong D; Department of Medicine, The University of Hong Kong, Hong Kong, China.
  • Schwabe C; Auckland Clinical Studies, Auckland, New Zealand.
  • Jackson K; Victorian Infectious Diseases Reference Laboratory, Victoria, Australia.
  • Lai CL; Department of Medicine, The University of Hong Kong, Hong Kong, China.
  • Gish RG; Hepatitis B Foundation, Doylestown, PA, USA.
  • Gane E; Auckland Clinical Studies, Auckland, New Zealand.
J Hepatol ; 77(5): 1287-1298, 2022 11.
Article de En | MEDLINE | ID: mdl-35870702

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite B chronique / Petit ARN interférent Limites: Humans Langue: En Journal: J Hepatol Sujet du journal: GASTROENTEROLOGIA Année: 2022 Type de document: Article

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Hépatite B chronique / Petit ARN interférent Limites: Humans Langue: En Journal: J Hepatol Sujet du journal: GASTROENTEROLOGIA Année: 2022 Type de document: Article