Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.

Cui, Zhifen; Zeng, Cong; Huang, Furong; Yuan, Fuwen; Yan, Jingyue; Zhao, Yue; Zhou, Yufan; Hankey, William; Jin, Victor X; Huang, Jiaoti; Staats, Herman F; Everitt, Jeffrey I; Sempowski, Gregory D; Wang, Hongyan; Dong, Yizhou; Liu, Shan-Lu; Wang, Qianben

Cui, Zhifen; Zeng, Cong; Huang, Furong; Yuan, Fuwen; Yan, Jingyue; Zhao, Yue; Zhou, Yufan; Hankey, William; Jin, Victor X; Huang, Jiaoti; Staats, Herman F; Everitt, Jeffrey I; Sempowski, Gregory D; Wang, Hongyan; Dong, Yizhou; Liu, Shan-Lu; Wang, Qianben.

Affiliation

Cui Z; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Zeng C; Viruses and Emerging Pathogens Program, Infectious Diseases Institute, Center for Retrovirus Research and Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA.
Huang F; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Yuan F; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Yan J; Division of Pharmaceutics and Pharmacology, College of Pharmacy and Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Zhao Y; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Zhou Y; Department of Pathology, College of Basic Medical Sciences and First Affiliated Hospital, China Medical University, Shenyang, China.
Hankey W; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Jin VX; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Huang J; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Staats HF; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Everitt JI; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Sempowski GD; Duke Human Vaccine Institute and Regional Biocontainment Laboratory, Duke University School of Medicine, Durham, NC, USA.
Wang H; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Dong Y; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
Liu SL; Duke Human Vaccine Institute and Regional Biocontainment Laboratory, Duke University School of Medicine, Durham, NC, USA.
Wang Q; Department of Pathology, Duke University School of Medicine, Durham, NC, USA.

Nat Chem Biol ; 18(10): 1056-1064, 2022 10.

Article de En | MEDLINE | ID: mdl-35879545

Sujet(s)

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Traitements médicamenteux de la COVID-19 Limites: Animals Langue: En Journal: Nat Chem Biol Sujet du journal: BIOLOGIA / QUIMICA Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

Texte intégral

Ajouter à My VHL

Imprimer

XML

PubMed Links

Recherche sur Google