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Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice.
Wang, Luyao; Yu, Yuanyuan; Ni, Shuaijian; Li, Dijie; Liu, Jin; Xie, Duoli; Chu, Hang Yin; Ren, Qing; Zhong, Chuanxin; Zhang, Ning; Li, Nanxi; Sun, Meiheng; Zhang, Zong-Kang; Zhuo, Zhenjian; Zhang, Huarui; Zhang, Shu; Li, Mei; Xia, Weibo; Zhang, Zhenlin; Chen, Lin; Shang, Peng; Pan, Xiaohua; Lu, Aiping; Zhang, Bao-Ting; Zhang, Ge.
Affiliation
  • Wang L; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Yu Y; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Ni S; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Li D; Institute of Integrated Bioinformedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Liu J; Northwestern Polytechnical University-Hong Kong Baptist University United Research Center of Space Musculoskeletal Health, Shenzhen, China.
  • Xie D; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Chu HY; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Ren Q; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhong C; Institute of Integrated Bioinformedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang N; Northwestern Polytechnical University-Hong Kong Baptist University United Research Center of Space Musculoskeletal Health, Shenzhen, China.
  • Li N; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Sun M; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Zhang ZK; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhuo Z; Institute of Integrated Bioinformedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang H; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang S; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Li M; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Xia W; Institute of Integrated Bioinformedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang Z; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Chen L; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Shang P; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Pan X; Institute of Integrated Bioinformedicine and Translational Science (IBTS), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Lu A; Law Sau Fai Institute for Advancing Translational Medicine in Bone and Joint Diseases (TMBJ), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
  • Zhang BT; Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery (HKAP), Hong Kong SAR, China.
  • Zhang G; Institute of Precision Medicine and Innovative Drug Discovery (PMID), School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Theranostics ; 12(13): 5645-5674, 2022.
Article de En | MEDLINE | ID: mdl-35966595
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ostéogenèse imparfaite / Maladies cardiovasculaires / Athérosclérose Type d'étude: Etiology_studies / Prognostic_studies / Risk_factors_studies Limites: Animals Langue: En Journal: Theranostics Année: 2022 Type de document: Article Pays d'affiliation: Chine Pays de publication: Australie
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ostéogenèse imparfaite / Maladies cardiovasculaires / Athérosclérose Type d'étude: Etiology_studies / Prognostic_studies / Risk_factors_studies Limites: Animals Langue: En Journal: Theranostics Année: 2022 Type de document: Article Pays d'affiliation: Chine Pays de publication: Australie