Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Poststroke Depression: A Systematic Review and Meta-Analysis.
Dis Markers
; 2022: 5911408, 2022.
Article
de En
| MEDLINE
| ID: mdl-35978885
ABSTRACT
Objectives:
Evidence shows that stroke-induced inflammatory responses play an essential role in the development of poststroke depression (PSD). The goal of this systematic review and meta-analysis was to critically evaluate the literature regarding the use of the neutrophil to lymphocyte ratio (NLR) as a reliable means to detect early PSD development, to help clinicians institute early interventions and improve outcomes.Methods:
Electronic databases, including Web of Science, PubMed, Google Scholar, and Scopus, were searched, and eight studies were included. We assessed the certainty of the associations with GRADE methods.Results:
We found that patients with PSD had higher NLR than the stroke patients with no depression (SMD = 0.51; CI 95% = 0.29-0.73, p < 0.001). Also, we found a significantly higher PLR in the patients with PSD when compared to the stroke patients with no depression (SMD = 0.66; CI 95% = 0.19-1.13, p < 0.001).Conclusion:
These findings indicated that NLR and PLR could be considered inexpensive biomarkers for the prediction of PSD.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Accident vasculaire cérébral
/
Granulocytes neutrophiles
Type d'étude:
Prognostic_studies
/
Systematic_reviews
Limites:
Humans
Langue:
En
Journal:
Dis Markers
Sujet du journal:
BIOQUIMICA
Année:
2022
Type de document:
Article
Pays d'affiliation:
Iran