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EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation.
Pribluda, Ariel; Daemen, Anneleen; Lima, Anthony Nelson; Wang, Xi; Hafner, Marc; Poon, Chungkee; Modrusan, Zora; Katakam, Anand Kumar; Foreman, Oded; Eastham, Jefferey; Hung, Jefferey; Haley, Benjamin; Garcia, Julia T; Jackson, Erica L; Junttila, Melissa R.
Affiliation
  • Pribluda A; Department of Translational Oncology, Genentech, Inc, South San Francisco, United States.
  • Daemen A; Department of Bioinformatics & Computational Biology, Genentech, Inc, South San Francisco, United States.
  • Lima AN; Department of Translational Oncology, Genentech, Inc, South San Francisco, United States.
  • Wang X; Department of Translational Oncology, Genentech, Inc, South San Francisco, United States.
  • Hafner M; Department of Bioinformatics & Computational Biology, Genentech, Inc, South San Francisco, United States.
  • Poon C; Department of Immunology, Genentech, Inc, South San Francisco, United States.
  • Modrusan Z; Department of Molecular Biology, Genentech, Inc, South San Francisco, United States.
  • Katakam AK; Department of Pathology, Genentech, Inc, South San Francisco, United States.
  • Foreman O; Department of Pathology, Genentech, Inc, South San Francisco, United States.
  • Eastham J; Department of Pathology, Genentech, Inc, South San Francisco, United States.
  • Hung J; Department of Pathology, Genentech, Inc, South San Francisco, United States.
  • Haley B; Department of Molecular Biology, Genentech, Inc, South San Francisco, United States.
  • Garcia JT; Department of Genetics, Stanford University, Stanford, United States.
  • Jackson EL; Department of Discovery Oncology, Genentech, Inc, South San Francisco, United States.
  • Junttila MR; Department of Translational Oncology, Genentech, Inc, South San Francisco, United States.
Elife ; 112022 08 19.
Article de En | MEDLINE | ID: mdl-35983994

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Adénocarcinome pulmonaire / Tumeurs du poumon Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Elife Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Adénocarcinome pulmonaire / Tumeurs du poumon Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Elife Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni