Opportunities and challenges in delivering biologics for Alzheimer's disease by low-intensity ultrasound.

Chen, Liyu; Cruz, Esteban; Oikari, Lotta E; Padmanabhan, Pranesh; Song, Jae; Götz, Jürgen

Chen, Liyu; Cruz, Esteban; Oikari, Lotta E; Padmanabhan, Pranesh; Song, Jae; Götz, Jürgen.

Affiliation

Chen L; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Cruz E; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Oikari LE; Cell and Molecular Biology Department, Mental Health and Neuroscience Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.
Padmanabhan P; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Song J; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
Götz J; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia. Electronic address: j.goetz@uq.edu.au.

Adv Drug Deliv Rev ; 189: 114517, 2022 10.

Article de En | MEDLINE | ID: mdl-36030018

Sujet(s)
Mots clés

Alzheimer's disease; Amyloid-ß; Bloodbrain barrier; Drug delivery; Focused (low-intensity) ultrasound; Immunotherapy; Microbubbles; Super-resolution microscopy; Tau; Tight junction

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Produits biologiques / Maladie d'Alzheimer Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Animals Langue: En Journal: Adv Drug Deliv Rev Sujet du journal: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Année: 2022 Type de document: Article Pays d'affiliation: Australie

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