Correction and Prevention of Hyponatremia in Patients With Cirrhosis and Ascites: Post Hoc Analysis of the ANSWER Study Database.
Am J Gastroenterol
; 118(1): 168-173, 2023 01 01.
Article
de En
| MEDLINE
| ID: mdl-36087106
ABSTRACT
INTRODUCTION:
We assessed the impact of long-term albumin administration to hyponatremic patients with ascites enrolled in the ANSWER trial.METHODS:
The normalization rate of baseline hyponatremia and the 18-month incidence rate of at least moderate hyponatremia were evaluated.RESULTS:
The hyponatremia normalization rate was higher with albumin than with standard medical treatment (45% vs 28%, P = 0.042 at 1 month). Long-term albumin ensured a lower incidence of at least moderate hyponatremia than standard medical treatment (incidence rate ratio 0.245 [CI 0.167-0.359], P < 0.001).DISCUSSION:
Long-term albumin administration improves hyponatremia and reduces episodes of at least moderate hyponatremia in outpatients with cirrhosis and ascites.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ascites
/
Albumines
/
Hyponatrémie
/
Cirrhose du foie
Limites:
Humans
Langue:
En
Journal:
Am J Gastroenterol
Année:
2023
Type de document:
Article
Pays d'affiliation:
Italie