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Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.
Llewellyn, Samantha V; Kermanizadeh, Ali; Ude, Victor; Jacobsen, Nicklas Raun; Conway, Gillian E; Shah, Ume-Kulsoom; Niemeijer, Marije; Moné, Martijn J; van de Water, Bob; Roy, Shambhu; Moritz, Wolfgang; Stone, Vicki; Jenkins, Gareth J S; Doak, Shareen H.
Affiliation
  • Llewellyn SV; In vitro Toxicology Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.
  • Kermanizadeh A; University of Derby, School of Human Sciences, Derby DE22 1GB, UK.
  • Ude V; Heriot Watt University, School of Engineering and Physical Sciences, Nano Safety Research Group, Edinburgh, UK.
  • Jacobsen NR; National Research Centre for the Working Environment (NRCWE), Lersø Parkallé 105, DK-2100 Copenhagen, Denmark.
  • Conway GE; In vitro Toxicology Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.
  • Shah UK; In vitro Toxicology Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.
  • Niemeijer M; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Leiden 2333 CC, the Netherlands.
  • Moné MJ; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Leiden 2333 CC, the Netherlands.
  • van de Water B; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Einsteinweg 55, Leiden 2333 CC, the Netherlands.
  • Roy S; MilliporeSigma, 14920 Broschart Road, Rockville, MD 20850, USA.
  • Moritz W; InSphero AG, Wagistrasse 27A, Schlieren, Switzerland.
  • Stone V; Heriot Watt University, School of Engineering and Physical Sciences, Nano Safety Research Group, Edinburgh, UK.
  • Jenkins GJS; In vitro Toxicology Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK.
  • Doak SH; In vitro Toxicology Group, Institute of Life Sciences, Swansea University Medical School, Swansea University, Singleton Park, Swansea, SA2 8PP, Wales, UK. Electronic address: S.H.Doak@swansea.ac.uk.
Toxicol In Vitro ; 85: 105473, 2022 Dec.
Article de En | MEDLINE | ID: mdl-36108805
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oxyde de zinc Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Toxicol In Vitro Sujet du journal: TOXICOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oxyde de zinc Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Toxicol In Vitro Sujet du journal: TOXICOLOGIA Année: 2022 Type de document: Article Pays d'affiliation: Royaume-Uni