Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues.

Reed, Ella; Fellows, Adam; Lu, Ruifang; Rienks, Marieke; Schmidt, Lukas; Yin, Xiaoke; Duregotti, Elisa; Brandt, Mona; Krasemann, Susanne; Hartmann, Kristin; Barallobre-Barreiro, Javier; Addison, Owen; Cuello, Friederike; Hansen, Arne; Mayr, Manuel

Reed, Ella; Fellows, Adam; Lu, Ruifang; Rienks, Marieke; Schmidt, Lukas; Yin, Xiaoke; Duregotti, Elisa; Brandt, Mona; Krasemann, Susanne; Hartmann, Kristin; Barallobre-Barreiro, Javier; Addison, Owen; Cuello, Friederike; Hansen, Arne; Mayr, Manuel.

Affiliation

Reed E; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Fellows A; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Lu R; National Heart and Lung Institute, Imperial College London, Du Cane Road, London W12 0NN, UK.
Rienks M; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Schmidt L; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Yin X; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Duregotti E; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Brandt M; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Krasemann S; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Hartmann K; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Lübeck/Kiel, University Medical Center Hamburg-Eppendorf, Germany.
Barallobre-Barreiro J; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Addison O; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Cuello F; King's British Heart Foundation Centre, School of Cardiovascular and Metabolic Medicine and Sciences, London SE5 9NU, UK.
Hansen A; Centre of Oral, Clinical & Translational Sciences, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, Guy's Hospital, London SE1 9RT, UK.
Mayr M; Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Matrix Biol Plus ; 16: 100122, 2022 Dec.

Article de En | MEDLINE | ID: mdl-36193159

Mots clés

2D, Two-dimensional; 3D cell culture; 3D, Three-dimensional; ADAMTS, A disintegrin and metalloproteinase with thrombospondin motifs; ALKi, Activin-like kinase inhibitor; Calcification; ECM; ECM, Extracellular matrix; EHT, Engineered heart tissue; EVT, Engineered vascular smooth muscle cell tissue; LC-MS/MS, Liquid chromatography with tandem mass spectrometry; Proteomics; SMC, Smooth muscle cell; Smooth muscle cells; TCP, Tissue culture polystyrene; TGFß-1, Transforming growth factor beta-1; Tissue engineering

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Prognostic_studies Langue: En Journal: Matrix Biol Plus Année: 2022 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: Pays-Bas

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