Intestine-specific removal of DAF-2 nearly doubles lifespan in Caenorhabditis elegans with little fitness cost.

Zhang, Yan-Ping; Zhang, Wen-Hong; Zhang, Pan; Li, Qi; Sun, Yue; Wang, Jia-Wen; Zhang, Shaobing O; Cai, Tao; Zhan, Cheng; Dong, Meng-Qiu

Zhang, Yan-Ping; Zhang, Wen-Hong; Zhang, Pan; Li, Qi; Sun, Yue; Wang, Jia-Wen; Zhang, Shaobing O; Cai, Tao; Zhan, Cheng; Dong, Meng-Qiu.

Affiliation

Zhang YP; National Institute of Biological Sciences, Beijing, Beijing, China.
Zhang WH; Beijing Key Laboratory of the Cell Biology of Animal Aging, Beijing, China.
Zhang P; National Institute of Biological Sciences, Beijing, Beijing, China.
Li Q; Beijing Key Laboratory of the Cell Biology of Animal Aging, Beijing, China.
Sun Y; National Institute of Biological Sciences, Beijing, Beijing, China.
Wang JW; Laboratory of Metabolic Genetics, College of Life Sciences, Capital Normal University, Beijing, China.
Zhang SO; National Institute of Biological Sciences, Beijing, Beijing, China.
Cai T; National Institute of Biological Sciences, Beijing, Beijing, China.
Zhan C; Laboratory of Metabolic Genetics, College of Life Sciences, Capital Normal University, Beijing, China.
Dong MQ; National Institute of Biological Sciences, Beijing, Beijing, China.

Nat Commun ; 13(1): 6339, 2022 10 25.

Article de En | MEDLINE | ID: mdl-36284093

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Caenorhabditis elegans / Protéines de Caenorhabditis elegans Type d'étude: Health_economic_evaluation Limites: Animals Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2022 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

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