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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium-Induced Colitis.
Jochum, Sarah B; Engen, Phillip A; Shaikh, Maliha; Naqib, Ankur; Wilber, Sherry; Raeisi, Shohreh; Zhang, Lijuan; Song, Shiwen; Sanzo, Gabriella; Chouhan, Vijit; Ko, Frank; Post, Zoe; Tran, Laura; Ramirez, Vivian; Green, Stefan J; Khazaie, Khashayarsha; Hayden, Dana M; Brown, Mark J; Voigt, Robin M; Forsyth, Christopher B; Keshavarzian, Ali; Swanson, Garth R.
Affiliation
  • Jochum SB; Department of Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Engen PA; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Shaikh M; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Naqib A; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Wilber S; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Raeisi S; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Zhang L; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Song S; Department of Pathology, GoPath Global Pathology Service, Buffalo Grove, IL, USA.
  • Sanzo G; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Chouhan V; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Ko F; Department of Cell and Molecular Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Post Z; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Tran L; Department of Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Ramirez V; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Green SJ; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Khazaie K; Genomics and Microbiome Core Facility, Rush University Medical Center, Chicago, IL, USA.
  • Hayden DM; Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN, USA.
  • Brown MJ; Division of Colon and Rectal Surgery, Department of Surgery, Rush University Medical Center, Chicago, IL, USA.
  • Voigt RM; Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH, USA.
  • Forsyth CB; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
  • Keshavarzian A; Department of Medicine, Rush University Medical Center, Chicago, IL, USA.
  • Swanson GR; Rush Center for Integrated Microbiome and Chronobiology Research, Rush Medical College, Rush University Medical Center, Chicago, IL, USA.
Inflamm Bowel Dis ; 29(3): 444-457, 2023 03 01.
Article de En | MEDLINE | ID: mdl-36287037
Disruption of peripheral circadian rhythms of the colon epithelium results in worse colitis and increased intestinal permeability in mice when given dextran sulfate sodium. This may be mediated through alterations in microbiota, butyrate levels, and STAT3.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Colite / Facteur de transcription STAT-3 Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Inflamm Bowel Dis Sujet du journal: GASTROENTEROLOGIA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Colite / Facteur de transcription STAT-3 Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Inflamm Bowel Dis Sujet du journal: GASTROENTEROLOGIA Année: 2023 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni