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TREM2 drives microglia response to amyloid-ß via SYK-dependent and -independent pathways.
Wang, Shoutang; Sudan, Raki; Peng, Vincent; Zhou, Yingyue; Du, Siling; Yuede, Carla M; Lei, Tingting; Hou, Jinchao; Cai, Zhangying; Cella, Marina; Nguyen, Khai; Poliani, Pietro L; Beatty, Wandy L; Chen, Yun; Cao, Siyan; Lin, Kent; Rodrigues, Cecilia; Ellebedy, Ali H; Gilfillan, Susan; Brown, Gordon D; Holtzman, David M; Brioschi, Simone; Colonna, Marco.
Affiliation
  • Wang S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Sudan R; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Peng V; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Zhou Y; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Du S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Yuede CM; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Lei T; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Hou J; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Cai Z; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Cella M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Nguyen K; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Poliani PL; Pathology Unit, Molecular and Translational Medicine Department, University of Brescia, Brescia 25123, Italy.
  • Beatty WL; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chen Y; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neurology, Knight Alzheimer's Disease Research Center, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Cao S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Lin K; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Rodrigues C; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, Devon EX4 4QD, UK.
  • Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Gilfillan S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Brown GD; Medical Research Council Centre for Medical Mycology, University of Exeter, Exeter, Devon EX4 4QD, UK.
  • Holtzman DM; Department of Neurology, Knight Alzheimer's Disease Research Center, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Brioschi S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Colonna M; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: mcolonna@wustl.edu.
Cell ; 185(22): 4153-4169.e19, 2022 10 27.
Article de En | MEDLINE | ID: mdl-36306735
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Microglie / Maladie d'Alzheimer Limites: Animals / Humans Langue: En Journal: Cell Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Microglie / Maladie d'Alzheimer Limites: Animals / Humans Langue: En Journal: Cell Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique