Left Ventricular Dysfunction Following the Ross-Konno Reconstruction is Independent of the Operation.
Pediatr Cardiol
; 44(2): 463-471, 2023 Feb.
Article
de En
| MEDLINE
| ID: mdl-36370189
ABSTRACT
The Ross-Konno (RK) operation is a well-established surgical treatment for combined left ventricular outflow tract obstruction and aortic valve pathology in children. Prior study has demonstrated that mechanical and electrical dyssynchrony exist post-RK compared to normal controls. The purpose of this study was to evaluate myocardial function pre- and post-RK as defined by echocardiography. Patients undergoing the RK operation (n = 13; median age 1.3 years; range 0.5-13.3 years) were evaluated by echocardiography at defined timepoints pre-RK, post-RK, 1-year post-RK, and 2 years post-RK. Defined parameters of left ventricular performance were analyzed systolic mechanical dyssynchrony (M-Dys), global left ventricular circumferential strain (GCS), and diastolic relaxation fraction (DRF). Patients with post-operative atrioventricular block (n = 6) were analyzed separately. No pre- versus post-RK differences existed in M-Dys, GCS, or DRF in patients both with and without post-RK atrioventricular block. Further, 1- and 2-year follow-up post-RK demonstrated significant heterogeneity in evaluated parameters of function with no pre- and post-RK differences in M-Dys, GCS, or DRF. Mechanical dyssynchrony exists post-RK reconstruction in both short- and long-term follow-up yet these echocardiographic parameters of ventricular performance are independent of the RK operation. Further study is, therefore, warranted to define causal relationships for observed short- and long-term ventricular dysfunction post-RK as the findings of the present study suggest a deleterious mechanism apart from the technical RK reconstruction.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Sténose aortique
/
Obstacle à l'éjection ventriculaire
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Dysfonction ventriculaire gauche
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Bloc atrioventriculaire
/
Procédures de chirurgie cardiaque
Limites:
Child
/
Humans
/
Infant
Langue:
En
Journal:
Pediatr Cardiol
Année:
2023
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique