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Sexual function of adult long-term survivors and their partners after allogeneic hematopoietic cell transplantation in Europe (S-FAST): a study from the Transplant Complications Working Party and Nurses Group of the EBMT.
Gjærde, Lars Klingen; Eeltink, Corien; Stringer, Jacqui; Mooyaart, Jarl; Bosman, Paul; Kenyon, Michelle; Liptrott, Sarah; Greenfield, Diana M; Linke, Andrea; Turlure, Pascal; Botti, Stefano; Dzaferagic, Dzenana; Sica, Simona; Welsh, Lorna; Kisch, Annika; Peric, Zinaida; Schoemans, Hélène; Murray, John.
Affiliation
  • Gjærde LK; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Eeltink C; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Stringer J; Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, Location VUMC, Amsterdam, The Netherlands.
  • Mooyaart J; The Christie NHS Trust, Manchester, UK.
  • Bosman P; University of Manchester, Manchester, UK.
  • Kenyon M; EBMT Statistical Unit, Leiden, The Netherlands.
  • Liptrott S; EBMT Data Office, Leiden, The Netherlands.
  • Greenfield DM; King's College Hospital NHS Foundation Trust, London, UK.
  • Linke A; Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
  • Turlure P; Sheffield Teaching Hospitals NHS Foundation Trust and The University of Sheffield, Sheffield, UK.
  • Botti S; EBMT Patient Advocacy Committee, EBMT Executive Office, Barcelona, Spain.
  • Dzaferagic D; CHU Limoges, Limoges, France.
  • Sica S; Azienda USL-IRCCS, Reggio Emilia, Italy.
  • Welsh L; University Hospital Center Rebro, Zagreb, Croatia.
  • Kisch A; Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Peric Z; Università Cattolica del Sacro Cuore, Rome, Italy.
  • Schoemans H; Gartnavel General Hospital, Glasgow, UK.
  • Murray J; Department of Haematology, Oncology and Radiation Physics, Skane University Hospital, Lund, Sweden.
Bone Marrow Transplant ; 58(2): 195-202, 2023 02.
Article de En | MEDLINE | ID: mdl-36376470
ABSTRACT
Sexual dysfunction after allogeneic hematopoietic cell transplantation (allo-HCT) is a common long-term complication. We conducted a European multicenter cross-sectional study of adult allo-HCT recipients who had survived >2 years and their partners to investigate sexual functioning after HCT and to evaluate whether discussion about sexual functioning between the transplant team and the survivor and partner was perceived to have taken place. In total, 136 survivors (77 males, 59 females) and 81 partners (34 males, 47 females) participated. Median age was 56 and 54 years in male and female survivors, respectively. Forty-seven percent of male and 65% of female survivors and 57% of male and 59% of female partners reported clinically relevant sexual problems. Sixty-two percent of survivors and 79% of partners reported that sexual functioning had not been discussed with them during transplant. Standardized sexual functioning scores were correlated with self-reported health status in survivors (rho = 0.24, p = 0.009). The high prevalence of sexual dysfunction warrants additional studies focusing on the impact of changes in sexuality for patients as well as their partners. Future studies should also investigate which methods that are effective in preventing or treating sexual problems after allo-HCT.
Sujet(s)

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Troubles sexuels d'origine physiologique / Transplantation de cellules souches hématopoïétiques Type d'étude: Clinical_trials / Observational_studies / Risk_factors_studies Aspects: Patient_preference Limites: Adult / Female / Humans / Male Langue: En Journal: Bone Marrow Transplant Sujet du journal: TRANSPLANTE Année: 2023 Type de document: Article Pays d'affiliation: Danemark

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Troubles sexuels d'origine physiologique / Transplantation de cellules souches hématopoïétiques Type d'étude: Clinical_trials / Observational_studies / Risk_factors_studies Aspects: Patient_preference Limites: Adult / Female / Humans / Male Langue: En Journal: Bone Marrow Transplant Sujet du journal: TRANSPLANTE Année: 2023 Type de document: Article Pays d'affiliation: Danemark