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Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans-chromosomic mouse line expressing human UGT2 enzymes.
Kobayashi, Kaoru; Deguchi, Tsuneo; Abe, Satoshi; Kajitani, Naoyo; Kazuki, Kanako; Takehara, Shoko; Nakamura, Kazuomi; Kurihara, Atsushi; Oshimura, Mitsuo; Kazuki, Yasuhiro.
Affiliation
  • Kobayashi K; Department of Biopharmaceutics, Graduate School of Clinical Pharmacy, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan.
  • Deguchi T; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Chuo-ku, Tokyo, Japan.
  • Abe S; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kajitani N; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kazuki K; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Takehara S; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Nakamura K; Advanced Medicine, Innovation and Clinical Research Center, Tottori University Hospital, Yonago, Tottori, Japan.
  • Kurihara A; Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Chuo-ku, Tokyo, Japan.
  • Oshimura M; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
  • Kazuki Y; Chromosome Engineering Research Center (CERC), Tottori University, Yonago, Tottori, Japan.
Pharmacol Res Perspect ; 10(6): e01030, 2022 12.
Article de En | MEDLINE | ID: mdl-36424908
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Zidovudine / Glucuronides Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Pharmacol Res Perspect Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Zidovudine / Glucuronides Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Pharmacol Res Perspect Année: 2022 Type de document: Article Pays d'affiliation: Japon Pays de publication: États-Unis d'Amérique