A comparative analysis of surgical outcome in uveitic and non-uveitic steroid-induced glaucoma in children.
Indian J Ophthalmol
; 70(12): 4218-4225, 2022 12.
Article
de En
| MEDLINE
| ID: mdl-36453318
ABSTRACT
Purpose:
To compare outcomes of surgical management of uveitic glaucoma (UG) and steroid-induced glaucoma (SIG) in children in terms of intraocular pressure (IOP) control, visual acuity, and associations for failure.Methods:
This was a retrospective case-control study of consecutive UG (cases) and non-uveitic SIG (controls) in children <18 years of age who underwent surgery between January 2005 and December 2017.Results:
Primary trabeculectomy with mitomycin C (MMC) was performed in 12 cases (mean age 9.2 ± 4.3 years) and 40 controls (mean age 10.4 ± 3.7 years) (P = 0.33). Primary phaco-trabeculectomy with MMC was performed in 11 cases (mean age 11.4 ± 4.7 years) and 16 controls (mean age 10.4 ± 3.4 years) (P = 0.57). IOP control (P = 0.26), visual acuity (P = 0.97), number of glaucoma medications (P = 0.06), and survival rates (49% cases vs. 68% controls at 5 years; P = 0.22) were similar between the two groups following trabeculectomy. Survival rates in the phaco-trabeculectomy group at 5 years were 68% cases vs. 69% controls (P = 0.71). IOP was higher (P = 0.008) and visual acuity was worse (P = 0.02) in cases at the last visit. Associations for failure (univariate analysis) were younger age (OR 6.29, 95% CL 1.43, 27.67; P = 0.03) and male gender (OR 4.79, 95% CL 1.09, 20.97; P = 0.04). On multivariate analysis, younger age (OR 11.985, 95% CL 1.071, 134.153; P = 0.04) remained significant. Preoperative number of uveitic attacks was protective on univariate (OR 0.75, 95% CL 0.48, 1.15; P = 0.1) and multivariate analyses (OR 0.49, 95% CL 0.24, 0.09; P = 0.04).Conclusion:
Outcomes of trabeculectomy between cases and controls were similar in our series. However, phaco-trabeculectomy in pediatric uveitic eye group fared worse than eyes with SIG.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Uvéite
/
Glaucome
Type d'étude:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Male
Langue:
En
Journal:
Indian J Ophthalmol
Année:
2022
Type de document:
Article
Pays d'affiliation:
Inde