Computationally-guided design and selection of high performing ribosomal active site mutants.

Kofman, Camila; Watkins, Andrew M; Kim, Do Soon; Willi, Jessica A; Wooldredge, Alexandra C; Karim, Ashty S; Das, Rhiju; Jewett, Michael C

Kofman, Camila; Watkins, Andrew M; Kim, Do Soon; Willi, Jessica A; Wooldredge, Alexandra C; Karim, Ashty S; Das, Rhiju; Jewett, Michael C.

Affiliation

Kofman C; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
Watkins AM; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
Kim DS; Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA.
Willi JA; Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Wooldredge AC; Prescient Design, Genentech, South San Francisco, CA 94080, USA.
Karim AS; Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
Das R; Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
Jewett MC; Center for Synthetic Biology, Northwestern University, Evanston, IL 60208, USA.

Nucleic Acids Res ; 50(22): 13143-13154, 2022 12 09.

Article de En | MEDLINE | ID: mdl-36484094

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Ribosomes / Peptidyl transferases Langue: En Journal: Nucleic Acids Res Année: 2022 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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