ML390 inhibits enterovirus 71 replication by targeting de novo pyrimidine biosynthesis pathway.

Yang, Qingyu; Wu, Chengyuan; Zhu, Guangyan; Ren, Fuli; Lin, Binbin; Huang, Rui; Hu, Xujuan; Zhao, Dingran; Peng, Ke; Wu, Ying; Wang, Qiongya; Huang, Chaolin; Zhang, Dingyu

Yang, Qingyu; Wu, Chengyuan; Zhu, Guangyan; Ren, Fuli; Lin, Binbin; Huang, Rui; Hu, Xujuan; Zhao, Dingran; Peng, Ke; Wu, Ying; Wang, Qiongya; Huang, Chaolin; Zhang, Dingyu.

Affiliation

Yang Q; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, 430023, China; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China.
Wu C; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China.
Zhu G; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China.
Ren F; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, 430023, China; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China; Wuhan Jinyintan Hospital,
Lin B; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230027, China.
Huang R; State Key Laboratory of Virology and Hubei Province Key Laboratory of Allergy and Immunology, Institute of Medical Virology, TaiKang Medical School, Wuhan University, Wuhan, 430071, China.
Hu X; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China.
Zhao D; State Key Laboratory of Virology and Hubei Province Key Laboratory of Allergy and Immunology, Institute of Medical Virology, TaiKang Medical School, Wuhan University, Wuhan, 430071, China.
Peng K; State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China; State Key Laboratory of Virology, CAS Key Laboratory of Special Pathogens, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, Chi
Wu Y; State Key Laboratory of Virology and Hubei Province Key Laboratory of Allergy and Immunology, Institute of Medical Virology, TaiKang Medical School, Wuhan University, Wuhan, 430071, China.
Wang Q; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China. Electronic address: 2432276106@qq.com.
Huang C; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, 430023, China; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China. Electronic address
Zhang D; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, Wuhan, 430023, China; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430023, China. Electronic address

Antiviral Res ; 209: 105498, 2023 01.

Article de En | MEDLINE | ID: mdl-36563943

Sujet(s)
Mots clés

And mouth disease; Antiviral; Dihydroorotate dehydrogenase; Enterovirus 71; Foot; Hand; de novo pyrimidine synthesis pathway

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Enterovirus / Entérovirus humain A / Infections à entérovirus / Syndrome mains-pieds-bouche Limites: Animals Langue: En Journal: Antiviral Res Année: 2023 Type de document: Article Pays d'affiliation: Chine Pays de publication: Pays-Bas

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