[Research advances on pharmacological interventions for hypertrophic scar].
Zhonghua Shao Shang Za Zhi
; 38(12): 1179-1184, 2022 Dec 20.
Article
de Zh
| MEDLINE
| ID: mdl-36594149
ABSTRACT
Hypertrophic scar is an abnormal fibrous proliferative disease that occurs after deep cutaneous injury, which not only affects aesthetics and function but also has negative psychological effects on the patients. However, the mechanism of hypertrophic scar formation has not been fully elucidated, and its clinical treatment is complex with a high rate of recurrence and no radicle cure. Intervention based on molecular targets will likely be the future direction for the prevention and treatment of hypertrophic scar. In this article, we review the specific roles and mechanisms of drug-targeted interventions in hypertrophic scar formation, including general drugs, cytokines, immunomodulators, herbal extracts, exosomes, and nanomaterials, in the context of advances in both basic and clinical research at home and abroad.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Cicatrice hypertrophique
Limites:
Humans
Langue:
Zh
Journal:
Zhonghua Shao Shang Za Zhi
Sujet du journal:
TRAUMATOLOGIA
Année:
2022
Type de document:
Article
Pays d'affiliation:
Chine