Ionic crosslinking of alginate/carboxymethyl chitosan fluorescent hydrogel for bacterial detection and sterilization.
Carbohydr Polym
; 302: 120427, 2023 Feb 15.
Article
de En
| MEDLINE
| ID: mdl-36604089
ABSTRACT
Herein, a polysaccharide-based fluorescent hydrogel with multi-responsiveness simply implemented by concurrent effects of ionic crosslinking/rehydration processes is presented. Specifically, the alginate and carboxymethyl chitosan are chosen to prepare the interpenetrating polymer matrix while a pair of metal cations has been selectively sequentially integrated to alter hydrogel mechanical and fluorescent properties. Experimental results indicate the hydrogels show tunable fluorescent emission in response to multiple cations and pH conditions, and display a reversible "ON/OFF" fluorescent response to Mn+/ethylenediaminetetraacetic acid. Moreover, this synergistic ionic crosslinking strategy is proved to be highly effective in preparing multifunctional metallohydrogels possessing robust/anisotropic mechanical properties, typical shape memory and cation/pH-responsive fluorescence performance, and a proof-of-application for bacterial detection and sterilization has also been demonstrated. Therefore, we believe this study would provide new insights into multifunctional luminescent hydrogels for advanced biomedical systems.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Chitosane
Type d'étude:
Diagnostic_studies
Langue:
En
Journal:
Carbohydr Polym
Année:
2023
Type de document:
Article