Discovery of inhibitors against SARS-CoV-2 main protease using fragment-based drug design.

Shao, Hai Ping; Wang, Tian Hua; Zhai, Hong Lin; Bi, Ke Xin; Zhao, Bing Qiang

Shao, Hai Ping; Wang, Tian Hua; Zhai, Hong Lin; Bi, Ke Xin; Zhao, Bing Qiang.

Affiliation

Shao HP; College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
Wang TH; College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
Zhai HL; College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China. Electronic address: zhaihl@163.com.
Bi KX; College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
Zhao BQ; College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.

Chem Biol Interact ; 371: 110352, 2023 Feb 01.

Article de En | MEDLINE | ID: mdl-36642317

Sujet(s)
Mots clés

Fragment-based drug discovery; Main protease; Molecular docking; Molecular dynamics; SARS-CoV-2

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Virus du SRAS / COVID-19 Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Chem Biol Interact Année: 2023 Type de document: Article Pays de publication: Irlande

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